Patho 1 | Nursing homework help

ALTERATIONS IN CELLULAR PROCESSES

At its core, pathology is the study of disease. Diseases occur for many reasons. But some, such as cystic fibrosis and Parkinson’s Disease, occur because of alterations that prevent cells from functioning normally.

Understanding of signals and symptoms of alterations in cellular processes is a critical step in diagnosis and treatment of many diseases. For the Advanced Practice Registered Nurse (APRN), this understanding can also help educate patients and guide them through their treatment plans.

For this Discussion, you examine a case study and explain the disease that is suggested. You examine the symptoms reported and explain the cells that are involved and potential alterations and impacts. 

RESOURCES

Be sure to review the Learning Resources before completing this activity. 
Click the weekly resources link to access the resources. 


WEEKLY RESOURCES

To prepare:

By Day 1 of this week, you will be assigned to a specific scenario for this Discussion. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.

BY DAY 3 OF WEEK 1

Post an explanation of the disease highlighted in the scenario you were provided. Include the following in your explanation:

· The role genetics plays in the disease.

· Why the patient is presenting with the specific symptoms described.

· The physiologic response to the stimulus presented in the scenario and why you think this response occurred.

· The cells that are involved in this process.

· How another characteristic (e.g., gender, genetics) would change your response.

Read a selection of your colleagues’ responses.

BY DAY 6 OF WEEK 1

Respond to 
at least two of your colleagues on 
2 different days and respectfully agree or disagree with your colleague’s assessment and explain your reasoning. In your explanation, include why their explanations make physiological sense or why they do not.

Note: For this Discussion, you are required to complete your initial post before you will be able to view and respond to your peers’ posting. Remember, once you click on Submit, you cannot delete or edit your own posts, and you cannot post anonymously. Please check your post carefully before clicking on Submit!

 

LEARNING RESOURCES


Lecturio Resources

·

Introduction to LecturioLinks to an external site.
 (9:04)

·

Lecturio Student Tools (PDF)

Download Lecturio Student Tools (PDF)

Review the following Video Resources and Content Pages in the Lecturio Platform by clicking button below labeled 
Load Week 1: Learning Resources in a new window.

· Basic Cell Housekeeping Functions (4:24 min)

· Subcellular Organization (4:57 min)

· Mechanisms of Cell Injury (7:06 min)

· Etiologies of Cellular Injury: Introduction (3:25 min)

· Chemical Agents – Etiologies of Cellular Injury (4:13 min)

· Hypoxia – Etiologies of Cellular Injury (2:25 min)

· Infectious Agents – Etiologies of Cellular Injury (3:21 min)

· ATP Depletion – Mechanisms of Cellular Injury (4:22)

· Overview of Cellular Injury (10:27 min)

· Mitochondria in Cellular Injury (1:11 min)

· Frameworks of Cellular Pathology (12:54 min)

· Classical Genetic Assumptions – Classic Mendelian Genetics (2:42 min)

· Anaphylaxis and Food Allergy (Hypersensitivity) in Children (7:13 min)

· Urticara (Hives) and Angioedema in Children (6:34 min)

If you have any technical issues, please contact the Customer Care Team at 1-800-925-3368. 

Please take a few minutes to share your experience with Lecturio: 

Optional Survey


Supplementary Resources

Note: These readings are intended to serve as supplementary to the Lecturio content provided in this course. Please refer/review these supplementary resources should you need help in reinforcing concepts and in preparation for completing this week’s Assessments.

· McCance, K. L. & Huether, S. E. (2019). 
Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.

· Chapter 1: Cellular Biology; Summary Review

· Chapter 2: Altered Cellular and Tissue Biology: Environmental Agents (pp. 46-61; begin again with Manifestations of Cellular Injury pp. 83-97); Summary Review

· Chapter 3: The Cellular Environment: Fluids and Electrolytes, Acids, and Bases

· Chapter 4: Genes and Genetic Diseases (stop at Elements of formal genetics); Summary Review

· Chapter 5: Genes, Environment-Lifestyle, and Common Diseases (stop at Genetics of common diseases); Summary Review

· Justiz-Vaillant, A. A., & Zito, P. M. (2019). 

Immediate hypersensitivity reactions

 Download Immediate hypersensitivity reactions. In 
StatPearls. Treasure Island, FL: StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/ 

Credit Line: Immediate Hypersensitivity Reactions – StatPearls – NCBI Bookshelf. (2019, June 18). Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/. Used with permission of Stat Pearls

Please see the below case studies for our discussion. You will need to choose a case to discuss. Keep this list handy since we will be referring to them throughout the term. 🙂

Week 1 Discussion

By Day 1 of Week 1, choose a case study scenario for this term.

Scenario 1:  Patient is a 22-year-old male who presents to the clinic for allergy immunotherapy “allergy shots”.  The patient is administered the medication the injection and waits 30 minutes to leave the center.  As the patient is leaving, he begins to complain of having difficulty swallowing, nausea, and feeling weak.  His vitals are 100/76, HR 120, Resp 24, O2 sat 95%.  The patient is now seating in a tripod position on the table.

Scenario 2:  Patient is an 18-year-old female with a diagnosis of cystic fibrosis who presents with complaints of increased productive cough and fatigue in the last few days.  The patient denies a fever but reports that her appetite hasn’t been good because she is so tired.  Patient vital signs:  BP 110/70, P 110, Res 28 labored, temp 98.4. Physical exam:  Lung sounds Diminished breath sounds bilateral lower lobes with crackles in upper lobes. 

Scenario 3:  Patient is a 48-year-old male with complaints of stiffness in his fingers that migrates to his upper arm joints and increased fatigue over the last few months.  The patient works in a bank and types frequently.  He commented that he thought he could have carpal tunnel syndrome, but the fatigue was beginning to worry him.  The patient reports a family history of rheumatoid arthritis.  He is currently taking Motrin for pain which partially relieves the symptoms.  He rates his pain a 5/10 at present, aching in both hands.  The patient’s vital signs are 120/80, Pulse 78, Res 16, Temp 100.1 F.  He denies any recent weight changes.  Physical exam reveals:  Edema to 4th and 5th PIP joints bilaterally with tenderness in the same joints.  His grip strength is decreased bilaterally. No edema of knees or ankles noted. 

Scenario 4:  Patient is a 42-year-old male who works as a carpenter with complaints of jerky involuntary movements which have become more pronounced in the last few months.  He first noticed that he was unable to grip his hammer at work.  He felt that his symptoms were related to caffeine intake in the beginning but have become worse and is now impacting his ability to perform his job duties.  He has been having some increased stress at home due to financial issues due to a possible work layoff.  His wife recommended he be seen for evaluation.  His paternal grandfather was diagnosed with Huntington’s disease at 48 years old.

Scenario 5:  Patient is a 38-year-old female who presents to the clinic with complaints of a wound to her right leg after a recent fall 5 days ago.  She reports that the area appeared to be healing and has now started getting red and has some dark colored drainage.  She denies any odor to the site.  She denies fever.  She has been cleaning the area with a wound spray and applying antibiotic ointment with a Band-Aid.  She reports that she has had some pain to the site 4/10 sharp at times. 

Just a reminder that APA 7th edition format is required. Please make sure to follow the proper format. Below are some resources to help you. If you need further assistance, please reach out to the Writing Center: 
https://academicguides.waldenu.edu/writingcenter
Links to an external site.

APA Resources:

https://apastyle.apa.org/instructional-aids/reference-examples.pdf
Links to an external site.

https://apastyle.apa.org/instructional-aids/reference-guide.pdf
Links to an external site.

https://apastyle.apa.org/style-grammar-guidelines/paper-format/student-annotated.pdf
Links to an external site.

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