Case Study: LM is an 86-year-old female admitted to the emergency department with delirium. Her spouse is with her and verifies that LM adheres to the medications she is currently prescribed. She does not self-monitor her BP or heart rate at home.

PMH:

· A Fib diagnosed 1 month ago

· HTN x 10 years

· CKD x 5 years

· Osteoarthritis x 7 years

· GERD x 20 years

Medications: 

· Digoxin 0.25 mg QD

· Metoprolol XL 25mg QD

· Warfarin 3 mg QD

· APAP 650 mg TID

· Omeprazole 20mg QD

· Multivitamin QD

Allergies: NKDA

Social History:

· Married to husband for 57 years

· No smoking, alcohol, limited daily exercise (short walks each morning)

Family History:

None reported

PE:

Elderly female with altered level of consciousness, no signs of bruising, bleeding, or other injury.

To Prepare

· Review the Resources for this module and consider the impact of potential pharmacotherapeutics for cardiovascular disorders introduced in the media piece.

· Review the case study assigned by your Instructor for this Assignment.

· Select one the following factors: genetics, gender, ethnicity, age, or behavior factors.

· Reflect on how the factor you selected might influence the patient’s pharmacokinetic and pharmacodynamic processes.

· Consider how changes in the pharmacokinetic and pharmacodynamic processes might impact the patient’s recommended drug therapy.

· Think about how you might improve the patient’s drug therapy plan based on the pharmacokinetic and pharmacodynamic changes. Reflect on whether you would modify the current drug treatment or provide an alternative treatment option for the patient.

BY DAY 7 OF WEEK 2

Write a 2- to 3-page paper that addresses the following:

· Explain how the factor you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned.

· Describe how changes in the processes might impact the patient’s recommended drug therapy. Be specific and provide examples.

· Explain how you might improve the patient’s drug therapy plan and explain why you would make these recommended improvements.